Cindella vs Rejuran: Light or Strength for the Skin?

A Mesotherapy Match Between Whitening and Regeneration

"I want brighter skin, but should I go for whitening or regeneration first?"

This is a common question among those considering mesotherapy for the first time. When you want to improve dull, uneven skin tone or get rid of that tired appearance, two representative injection treatments often come up—Cindella and Rejuran. Both are extremely popular products in the field of mesotherapy, but their effects and mechanisms of action are quite different.

Today, we’ll kindly guide you through the characteristics of each, what effects you can expect, which skin types they’re best suited for, and how the treatments are administered—explained in a way that’s easy for mesotherapy beginners to understand.

Who Typically Seeks These Treatments?

Cindella is often chosen by individuals who

• Feel their skin has become noticeably dull recently

• Struggle with pigmentation caused by UV exposure or stress

• Have uneven skin tone and a generally dark complexion

• Want to restore radiance and a clear impression to their face

Rejuran is recommended for those who

• Are concerned about loss of elasticity, fine lines, and thinning skin

• Want to restore a compromised skin barrier due to acne or external irritation

• Desire deeper structural regeneration and improvement from within

What Are the Main Differences Between Cindella and Rejuran?

Category	Cindella	Rejuran
Primary Purpose	Whitening, Antioxidation	Skin regeneration, Elasticity enhancement
Key Ingredients	Glutathione, Alpha Lipoic Acid (ALA), Vitamin C	Polynucleotide (PN, salmon DNA)
Post-Treatment Feel	Brighter, more luminous skin tone	A sense of inner fullness, organized texture
Onset of Results	Brighter tone within 1–2 days	Visible improvement in texture within 1–2 weeks
Treatment Frequency	Once a week × 3–5 sessions recommended	Around 2–4 sessions recommended

Cindella, a representative “whitening injection,” does not literally make the skin white but instead reduces oxidative stress, making the skin look clearer and more translucent.Rejuran, in contrast, provides polynucleotide-based ingredients that promote dermal regeneration at the DNA level, restoring the skin’s inherent ability to repair itself and strengthening weakened tissue.

Recommended Dosage by Area (Aesthetic Perspective)

• Cindella: 2–4ml for full face (up to 5ml if including neck)

• Rejuran: 2ml for full face; if dividing by area, inject 0.2–0.4ml per point in multiple sessions

Syringe Specifications and Dilution Method

Cindella

• Typically uses 1ml or 2.5ml syringes

• Can be mixed with normal saline or vitamin C ampoules

• Dilution ratio: use undiluted or dilute 1:1 with saline

Rejuran

• Administered with 1ml syringes and 33G–34G ultra-fine needles

• Used undiluted

• Injected using multipoint (intradermal papule) technique according to skin condition

Pre-Treatment Preparation

• Avoid alcohol, intense exercise, and saunas for at least one day before treatment

• If active inflammation or acne is present, it is advisable to calm the skin before proceeding

• On the day of treatment, cleanse gently and apply topical anesthetic cream for pain relief

Injection Technique Summary

• Cindella is injected evenly into the dermis or just below using a wide dispersion technique. It is not deeply injected. It’s commonly delivered with a meso-gun or insulin syringe, ensuring wide coverage with a fine mist-like distribution.

• Rejuran is administered using the intradermal papule (multipoint microinjection) method, in which small amounts are injected into multiple points. Although this can cause a slightly bumpy appearance initially, it is absorbed within 1–2 days and effectively stimulates deep skin regeneration.

Q: Should I Choose Whitening or Regeneration First?

There is no one-size-fits-all answer. However, if the skin barrier is significantly damaged, start with regeneration. If your biggest concern is uneven skin tone and dullness, whitening may be a better starting point.

Both treatments can also be combined. In practice, many clinics alternate between Cindella and Rejuran every 2 weeks.

Common Post-Treatment Questions

• Q. Can I use both products together?

  
  

  → Yes, many clinics alternate Cindella and Rejuran every 2 weeks. Since their functions differ, they can work synergistically.

• Q. How long do the effects last?

  
  

  → Cindella yields quick tone-up results but requires consistent maintenance. Rejuran, after 3–4 sessions, can be maintained with quarterly follow-ups.

• Q. Are there similar alternatives?

  
  

  → Cindella can be substituted with White Toning or a Vitamin C+ALA cocktail. Rejuran can be substituted with PN+HA combinations or exosome-based treatments.

• Q. How should I manage after treatment?

  
  

  → Cindella requires minimal aftercare—just proper hydration and sun protection. Rejuran benefits from the use of healing ointments or soothing skin care.

Cindella vs Rejuran — At a Glance Summary

Category	Cindella	Rejuran
Immediate Effects	Brighter tone, refined skin texture	Slight volumizing effect, improved plumpness
Long-Term Benefits	Pigmentation reduction	Dermal regeneration, elasticity improvement
Compatibility Together	Excellent (functions differ)	Excellent
Sensitive Skin Tolerance	Generally safe	Very gentle, but consult for ultra-sensitive skin
Ingredient Complexity	ALA, Vit C and more	Pure high-grade PN-based
Use with Skin Boosters	Creates synergy	Compatible but avoid injecting in the same layer

Cindella and Rejuran approach skin improvement from different angles, but both ultimately aim for radiant and healthy skin. If you're unsure whether whitening or regeneration should come first, the best starting point is to get an accurate skin diagnosis and build a personalized treatment plan from there.